Products

MANUFACTURED PRODUCTS

HAVAX®Hepatitis A Vaccine

Hepatitis A virus (HM 175 hepatitis A strain) is propagated on primary monkey kidney cell cultures to produce this vaccine. Aer purification from cell lysates, the HAV preparation is formaldehyde-inactivated. The vaccine is adjuvanted by adsorption to aluminum hydroxide. HAVAX is used for the prevention of Hepatitis A virus infection.

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Gene-HBvax is a recombinant Hepatitis B vaccine used to prevent Hepatitis B virus infection. This vaccine utilizes the surface antigen of the Hepatitis B virus (HBV) obtained through culturing genetically engineered Hansenula polymorpha yeast cells containing the HBV surface antigen gene. The Hepatitis B surface antigen (HBsAg) is purified through various chemical processes, including ultracentrifugation, column chromatography, and formaldehyde treatment.

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JEVAX is a result of technology transfer from the BIKEN Institute, Osaka University, Japan. It is an inactivated purified vaccine derived from mouse-brain tissue infected with the Japanese encephalitis virus (Nakayama strain). The vaccine production involves harvesting mouse brains before the onset of encephalitis symptoms, triturating them in a buffered solution, and then centrifuging the mixture. The obtained supernatants are treated with protamine sulfate, formaldehyde-inactivated, and purified through ultracentrifugation.

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MANUFACTURED PRODUCTS

mORCVAXOral cholera vaccine

The vaccine is a liquid formulation of oral Cholera vaccine containing O1 (consisting of V.Cholerae classical type and Eltor) and O139 of Vibrio cholerae inactivated with either heat or formaldehyde. The manufacturing process consists of following steps: culture in appropriate medium, inactivate by formaldehyde or heat, concentrate by centrifugation or filtration, remove cholera toxin. The formulation of final bulk is calculated by Lipopolysaccharide (LPS) content to ensure concentration of the antigens required to stimulate immunogenicity for the prevention of cholera disease.

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MANUFACTURED PRODUCTS

SKYVARICELLA(Updating)

Produced by SK Bioscience of Korea, SKYVaricella is a live attenuated vaccine containing the Oka/SK strain of the varicella-zoster virus. The vaccine is produced in MRC-5 cell lines. It is supplied as an injection solution with a lyophilized white crystalline pellet included in a clear vial. Upon reconstitution with the attached solvent, it forms a colorless or pale-ellow liquid.

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IMPORTED PRODUCTS

VA-MENGOC-BC

Produced by the Instituto Finlay de Vacunas in Cuba, VA-MENGOC-BC is a complex vaccine comprising purified outer membrane vesicles of serogroup B and purified capsular polysaccharide of serogroup C meningococcus, adsorbed onto aluminum hydroxide gel. It is indicated for active immunization against Meningococcal disease caused by serogroups B and C. Its use is recommended for individuals from 6 months to 45 years old of aged, particularly in areas with a high risk of meningococcal disease transmission.

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Produced by the Serum Institute of India Pvt. Ltd., this vaccine is prepared from live, attenuated strains of Edmonston-Zagreb measles virus, Leningrad-Zagreb (L-Z) mumps virus, and Wistar RA 27/3 rubella virus. The measles and rubella viruses are propagated on human diploid cells (HDC), while the mumps virus is grown on chick fibroblasts from SPF eggs (Specific Pathogen-Free). The vaccine is supplied as a freeze-dried product and is provided with diluent

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IMPORTED PRODUCTS

PENTAVAC

Produced by the Serum Institute of India Pvt. Ltd., this vaccine is a liquid conjugate vaccine adsorbed. This vaccine is currently being provided in the Expanded Program on Immunization since 2018 to prevent dangerous infectious diseases including diphtheria, tetanus, pertussis, hepatitis B and pneumonia/purulent meningitis caused by Hib bacteria.

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